Translational studies led by research faculty in the Center for Cognitive Neurology explore new treatments for neurologic disorders such as Alzheimer’s disease.

Alterations in Ventral Hippocampal CA1 Processing as a Mechanism for Anxiety in Alzheimer’s Disease
Principal investigator: Arjun V. Masurkar, MD, PhD

Differential Impact of Alzheimer’s Disease on Neuronal Subpopulations in Dorsal Hippocampal CA1
Principal investigator: Arjun V. Masurkar, MD, PhD

Mechanisms of Peroxiredoxin 6 Endowed Protection in Alzheimer’s Disease
Principal investigator: Martin Sadowski, MD, PhD

Role of Microglia in Neurodegeneration-Effect of ApoE
Principal investigator: Martin Sadowski, MD, PhD

Innate Immunity Stimulation Effects on Biomarkers, Cognition, and the Vascular Amyloid Proteome in a Squirrel Monkey Model of Sporadic CAA
Principal investigator: Henrieta Scholtzova, MD, PhD

Characterization of Biomarkers and the Vascular Amyloid Proteome in a Non-human Primate Model of Alzheimer’s Disease
Principal investigator: Henrieta Scholtzova, MD, PhD

Early, Pre-Clinical Inflammation and NGF Dysmetabolism in DS
Multiple principal investigator: Thomas M. Wisniewski, MD

Novel Approaches to Understand the Pathogenesis and Treat Alzheimer’s Disease
Principal investigator: Thomas M. Wisniewski, MD