Education

• Medical Education: King's College, London
• Internship: Residency in Pathology, Downstate Medical Center 1984-1985; Residency in Neurology, New York University Medical Center 1985-1988
• Clinical Fellowship: Clinical and Basic Research Neuropathology Fellowship, Columbia Presbyterian Medical Center 1988-1990

About Dr. Wisniewski

Dr. Wisniewski specializes in the diagnosis and manangement of age associated memory problems, mild cognitive impairment, Alzheimer's disease, vascular dementia, fronto-temporal dementia, prion disease and other neurodegenerative disorders resulting in cognitive impairment.

Dr. Wisniewski obtained his MD at Kings College School of Medicine in the UK. He did his Neurology and Neuropathology Residencies at NYU and Columbia-Presbyterian, respectively. He is a board certified Neurologist and Neuropathologist, who runs an active research laboratory focusing on neurodegenerative disorders, in particular the mechanisms which drive amyloid deposition in Alzheimer''s and prion related diseases. This work has lead to over 170 peer-reviewed publications. An important aim of his work has been to direct this greater understanding toward therapeutic interventions. Key discoveries have included discovering the role of apolipoprotein E in driving amyloid deposition in late-onset AD. Dr. Wisniewski coined the term "pathological chaperone" to denote the role of apoE, even prior to the discovery of the linkage of apoE4 to late-onset AD. More recently, Dr. Wisniewski has been developing strategies for the removal of amyloid both in AD using non-toxic, highly immunogenic proteins as "vaccines". This approach has been shown to be efficacious in both animal models of AD and prion disease.

Diseases and conditions treated

• Alzheimer's Disease
• Mild Cognitive Impairment
• Vascular Dementia
• Pick's Disease
• Fronto-temporal Dementia
• Prion Disease
• Age-associated Memory Loss
• Neurodegenerative disorders resulting in cognitive impairment